The brain is the central organ needed for all body activities that sustain life. It is made of neurons (brain cells) that have one main job, which is to pass on signals, messages and instructions to each other. This communication network gives us memory, cognition, speech and control of movement.
Diseases disturb brain function by making cells produce abnormal proteins, causing hormone abnormalities, infections, or other mechanisms.
Regardless of the cause, different attacks and abnormalities cause the same responses in cells. One such response in our body is called inflammation.
Inflammation increases blood flow, increases body temperature, and brings immune cells to the area that is under attack. This is useful to fight bacteria and viruses that cause colds and infections.
However, inflammation can also cause more harm to the body by preventing cells from doing their normal jobs.
If the cause of the disease stays in the brain for a long time, the brain will be continuously inflamed. For example in Alzheimer’s disease, abnormal proteins build up in the brain, and patients have chronic inflammation in the brain. Long-term inflammation can prevent cells from normal cell activity and attempting repair, which further contributes to further brain damage and worsening symptoms.
Marine polyphenols are naturally occurring substances with potential therapeutic and protective effects in the brain. Biomedical research suggests several possible mechanisms of treatment:
1) Decrease production of β-amyloid proteins that form abnormal clusters, and inhibit their clustering. β-amyloid clusters are the hallmark of Alzheimer’s disease.
2) Inhibits inflammation. Inflammation is caused by chemicals that produce stress responses in cells. Without intervention, inflammation feeds forward to cause more and more inflammatory chemicals and more stressed cells. Marine polyphenols decrease inflammatory chemicals and prevent them from reaching the level of irreversible damage to neurons.
3) Restore acetylcholine (chemical signals) and cholinergic transmission (neuron communication), which are decreased in Alzheimer’s and Parkinson’s disease.
4) Can cross the blood-brain barrier and remain stable in the brain.
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